学习生物的英语达人帮帮忙翻译下这一小段呗,我读了很多遍了,大致的意思是懂了,就是还是很模糊。

还是不能彻底领悟其中的意思,望指导!麻烦您帮忙一下。不胜感激。Asymmetric segregation of polarized antigen on B cell division shapes presentation capacity .During the activation of humoral immune responses ,B cells acquire antigen for subsequent presentation to cognate T cells .Here we show that after mouse B cells accumulate antigen , it is maintained in a polarized distribution for extended periods in vivo. Using high—throughput imaging flow cytometry, we observed that this polarization is preserved during B cell division , promoting asymmetric antigen segregation among progeny . Antigen inheritance correlates with the ability of progency to activate T cells :Daughter cells receiving larger antigen stores exhibit a prolonged capacity to present antigen which renders them more effective in competing for T cell help. The generation of progeny with differential capacities for antigen presentation may have implications for somatic hypermutation and class switching during affinity maturation and as B cells commit to effector cell fates.谢谢大家了。
2026年09月25日 13:35
有3个网友回答
网友(1):

非对称隔离的偏振抗原对B细胞分裂形状表示能力。
在激活体液免疫反应、B细胞获得抗原随后的演讲来同源T细胞。在此我们发现小鼠的B细胞抗原后积累,保持在两极分化期的延长体内分布。利用高通量成像流式细胞术,我们观察到这种分化是B细胞分裂期间保留,促进非对称抗原之间的种族隔离现象的后代。抗原继承与progency的能力来激活T细胞:女儿细胞接受更大的抗原商店展示一个长期能力呈现抗原将更加有效,在争夺T细胞的帮助。后代的生成与微分能力抗原的表述会对高突变率体细胞和类切换在B细胞的成熟和亲和力是致力于效应细胞的命运。

网友(2):

1

网友(3):

不对称的分离细胞极化抗原分形状表现能力。

在激活的体液免疫应答,细胞获取抗原随后介绍同源细胞。在这里,我们表明,在小鼠细胞积累抗原,这是保持在一个极长时间在体内的分布。利用高通量流式细胞仪成像,我们观察到这种两极分化是保存在细胞分裂,促进不对称抗原之间的隔离后代。抗原继承相关的能力的子体激活细胞子细胞接收大容量存储的长期展览抗原呈递抗原,使他们更有效地竞争细胞帮助。代后代鉴别能力为抗原提呈可能影响体突变和阶级开关在亲和力成熟和细胞效应细胞命运的承诺。