1 make sth(直接加宾语) possible: Hard work plus a little wisdom has made John's success possible (直接加宾语)
2 make it(只能用it) possible for sb. to do sth.或者make it possble that 加句子
如:A) Hard work plus a little wisdom has made it possible for John to succeed in his job.
B) Hard work with a little wisdom made it possible that John succeeded in his job.
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